梭菌正丁醇代谢工程研究进展
Recent advances in metabolic engineering of clostridia for n-butanol production
（图中所示基因表达的酶：pfk—6-磷酸果糖激酶；fba—果糖-二磷酸醛缩酶；pyk—丙酮酸激酶；ilvB—乙酰乳酸合酶；aldc—乙酰乳酸脱羧酶；acr—乙偶姻还原酶；pfor—丙酮酸-铁氧还蛋白氧化酶；hyd—氢酶；pta—乙酰基磷酸转移酶；ack—乙酸激酶；thl—硫解酶；hbd—3-羟基丁酰CoA脱氢酶；crt—巴豆酸酶；bcd—丁酰CoA脱氢酶；ter—反式烯酰辅酶A还原酶；ptb—磷酸丁酰转移酶；buk—丁酸激酶；ctfAB—乙酰乙酰CoA：乙酸/丁酸：CoA转移酶；adc—乙酰乙酸脱羧酶；sadh—异丙醇脱氢酶；adh—乙醇脱氢酶；bdh/edh—丁醇/乙醇脱氢酶；adhE—醇/醛脱氢酶）
(pfk—6-phosphofructokinase; fba—fructose-bisphosphate aldolase; pyk—pyruvate kinase; ilvB—acetolactate synthase; aldc—acetolactate decarboxylase; acr—acetoin reductase; pfor—pyruvate-ferredoxin oxidoreductase; hyd—hydrogenase; pta—phosphate acyltransferase; ack—acetate kinase; thl—thiolase; hbd—3-hydroxybutyryl-CoA dehydrogenase; crt—crotonase; bcd—butyryl-CoA dehydrogenase; ter—trans-enoyl-CoA reductase; ptb—phosphobutyryl transferase; buk—butyrate kinase; ctfAB—acetoacetyl-CoA: acetate/butyrate: CoA transferase; adc—acetoacetate decarboxylase; sadh—isopropanol dehydrogenase; adh/edh—alcohol/ehanol dehydrogenase; bdh/edh—butanol/ehanol dehydrogenase; adhE—alcohol/aldehyde dehydrogenase)
