利用异源表达挖掘纤维堆囊菌So0157-2的新型天然产物
周海波, 申琪瑶, 陈汉娜, 王宗杰, 李越中, 张友明, 卞小莹

Genome mining for novel natural products in Sorangium cellulosum So0157-2 by heterologous expression
ZHOU Haibo, SHEN Qiyao, CHEN Hanna, WANG Zongjie, LI Yuezhong, ZHANG Youming, BIAN Xiaoying
表4 化合物1～3的NMR核磁数据
Tab. 4 1H (500 MHz) and 13C (125 MHz) data of 1～3 in DMSO-d6
No123
δCδH (J in Hz)δH (J in Hz)δH (J in Hz)
N-Me-Leu

1

2

3

4

5

6

N-Me

167.6, C

59.2, CH

42.7, CH2

25.1, CH

23.1, CH3

21.8, CH3

32.1, CH3

3.78, dd (4.5, 8.2)

1.58, m

1.87, m

0.89, d (6.7)

0.93, d (6.7)

2.82, s

3.79, t (6.7)

1.59, t (7.0)

1.79, m

0.90, d (6.5)

0.93, d (6.5)

2.82, s

3.78, dd (4.5, 8.1)

1.58, m

1.87, m

0.89, d (6.5)

0.93, d (6.5)

2.82, s

Val/Leu/Ile

1

2

3

4

5

6

NH

165.1, C

60.1, CH

32.6, CH

19.2, CH3

18.1, CH3

3.55, dd (3.6, 5.2)

2.01, m

0.92, d (6.8)

0.84, d (6.8)

8.24, d (2.4)

3.73, dt (3.9, 8.7)

1.52, m

1.45, m

1.79, m

0.86, d (6.5)

0.90, d (6.5)

8.39, d (2.6)

3.61, dd (3.8, 4.8)

1.73, m

1.43, m

1.11, m

0.84, t (6.5)

0.89, d (6.5)

8.23, d (1.6)