定向进化在蛋白质工程中的应用研究进展

祁延萍, 朱晋, 张凯, 刘彤, 王雅婕

Recent development of directed evolution in protein engineering

QI Yanping, ZHU Jin, ZHANG Kai, LIU Tong, WANG Yajie

图 13 Aldolase催化的可逆羟醛缩合反应及β-羰基酮与氨基酸残基形成乙烯基酰胺的催化抑制机理

Fig. 13 Aldolase-catalyzed reversible aldol condensation reaction and the catalytic inhibition mechanism of β-carbonyl ketones with amino acid residues to form vinyl amides