代谢工程改造微生物利用甲酸研究进展
Progress in metabolic engineering of microorganisms for the utilization of formate
（绿色底色的化合物为路径底物，粉色底色的化合物为路径产物）Ack—乙酸激酶；Acs—乙酰辅酶A合成酶；COdh—CO脱氢酶；CoFeSP—钴铁硫蛋白；Eno—烯醇化酶；Fch—次甲基四氢叶酸环水解酶；Fdh—甲酸脱氢酶；Ftl—甲酸四氢叶酸连接酶；Fts—甲酰四氢叶酸合成酶；Gapdh—3-磷酸甘油醛脱氢酶；GCS—甘氨酸裂解系统；Gk—甘油酸激酶；GlyA—丝氨酸羟甲基转移酶；GR—甘氨酸还原酶复合体；Hpr—羟基丙酮还原酶；Madh—苹果酸脱氢酶；Mcl—苹果酰辅酶A裂解酶；Metr—甲基转移酶；Mtd—亚甲基四氢叶酸脱氢酶；Mtk—苹果酸裂解酶；Mtr—亚甲基四氢叶酸还原酶；PFOR—丙酮酸铁氧还蛋白氧化还原酶；Pgk—磷酸甘油酸激酶；Ppc—PEP羧化酶；Prk—磷酸核酮糖激酶；Rubisco—核酮糖-1，5-二磷酸羧化酶/加氧酶；Sda—丝氨酸脱氨酶；Sgt—丝氨酸-乙醛酸转氨酶；THF—四氢叶酸
(compounds with a green background are pathway substrates; compounds with a pink background are pathway products) Ack—Acetate kinase; Acs—acetyl-CoA synthase; COdh—CO dehydrogenase; CoFeSP—corrinoid ironsulfur protein; Eno—enolase; Fch—methenyl-tetrahydrofolate cyclohydrolase; Fdh—formate dehydrogenase; Ftl—formate-tetrahydrofolate ligase; Fts—formyl-tetrahydrofolate synthetase; Gapdh—glyceraldehyde-3-phosphate dehydrogenase; GCS—glycine cleavage system; Gk—glycerate kinase; GlyA—serine hydroxymethyltransferase; GR—Glycine reductase complex; Hpr—hydroxypyruvate reductase; Madh—malate dehydrogenase; Mcl—malyl-CoA lyase; Metr—methyltransferase; Mtd—methylene-tetrahydrofolate dehydrogenase; Mtk—malate thiokinase; Mtr—methylene-tetrahydrofolate reductase; PFOR—Pyruvate ferredoxin oxidoreductase; Pgk—Phosphoglycerate kinase; Ppc—phosphoenolpyruvate carboxylase; Prk—phosphoribulo kinase; Rubisco—Ribulose-1,5-bisphosphate carboxylase/oxygenase; Sda—serine deaminase; Sgt—serine-glyoxylate transaminase; THF—tetrahydrofolate
