代谢工程改造微生物利用甲酸研究进展

程真真, 张健, 高聪, 刘立明, 陈修来

Progress in metabolic engineering of microorganisms for the utilization of formate

CHENG Zhenzhen, ZHANG Jian, GAO Cong, LIU Liming, CHEN Xiulai

图5 人工设计甲酸利用路径 Acdh—乙醛脱氢酶；Acs—乙酰辅酶A合成酶；Acps—乙酰磷酸合成酶；Dhak—二羟基丙酮激酶；Fls—甲醛酶；Gals—乙醇醛合成酶；Pta—磷酸转乙酰酶（绿色底色的化合物为路径底物，粉色底色的化合物为路径产物）

Fig. 5 Artificial formate-utilizing pathways Acdh—acetaldehyde dehydrogenase; Acs—acetyl-CoA synthase; Acps—acetyl phosphate synthase; Dhak—dihydroxyacetone kinase; Fls—formolase; Gals—glycolaldehyde synthase; Pta—phosphate acetyltransferase (compounds with a green background are pathway substrates, compounds with a pink background are pathway products)