黄酮类化合物生物合成及其在化妆品中应用的研究

韦灵珍, 王佳, 孙新晓, 袁其朋, 申晓林

Biosynthesis of flavonoids and their application in cosmetics

Lingzhen WEI, Jia WANG, Xinxiao SUN, Qipeng YUAN, Xiaolin SHEN

图1 黄酮类化合物的天然合成途径 ［PAL，苯丙氨酸解氨酶；C4H，肉桂酸4-羟化酶；TAL，酪氨酸解氨酶；4CL，4-香豆酸辅酶A连接酶；CHS，查尔酮合酶；CHR，查尔酮还原酶；CHI，查尔酮异构酶；FNS，黄酮合酶；F3’H，黄烷酮-3'-羟化酶；F3H，黄烷酮-3-羟化酶；F3'5'H，黄烷酮-3'，5'-羟化酶；FLS，黄酮醇合酶；UGT，UDP-葡萄糖基转移酶；RhaT，鼠李糖转移酶；DFR，二氢黄酮醇4-还原酶；ANS，花青素合酶；UF3GT，黄酮类化合物3-O-葡萄糖基转移酶；C3G，矢车菊素3-O-葡萄糖苷；P3G，天竺葵素-3-O-葡萄糖苷；D3G，飞燕草素-3-O-葡萄糖苷］

Fig. 1 Natural synthesis pathways of flavonoids (PAL, Phenylalaninammo-nialyase; C4H, Cinnamic acid-4-hydroxylase; TAL,Tyrosine ammonialyase; 4CL, 4-Coumarate coenzyme A ligase; CHS, Chalcone synthase; CHR, Chalcone reductase; CHI, Chalcone isomerase; FNS, Flavone synthase; F3'H, Flavanone 3'-β-hydroxyalse; F3H, Flavanone 3-β-hydroxyalse; F3'5'H, Flavanone 3',5'-β-hydroxyalse; FLS, Flavonol synthase; UGT, UDP-Glycosyltransferase; RhaT, Rhamnose transferase; DFR, Dihydroflavonol 4-reductase; ANS, Anthocyanidin synthase; UF3GT, Flavonoid 3-O-glycosyltransferase;C3G, Cyanidin 3-O-glucoside chloride; P3G, Pelargonidin3-O-glucoside;D3G, Delphinidin-3-O-glucoside)