L-精氨酸的微生物合成研究进展

王倩, 果士婷, 辛波, 钟成, 王钰

Recent advances in biosynthesis of L-arginine using engineered microorganisms

Qian WANG, Shiting Guo, Bo XIN, Cheng ZHONG, Yu WANG

图1 微生物中L-精氨酸生物合成途径 （ArgA：乙酰谷氨酸合成酶；ArgB：乙酰谷氨酸激酶；ArgC：乙酰谷氨酰磷酸还原酶；ArgD：乙酰鸟氨酸转氨酶；ArgE：乙酰鸟氨酸脱乙酰基酶；ArgF：鸟氨酸氨甲酰转移酶；ArgG：精氨酸琥珀酸合成酶；ArgH：精氨酸琥珀酸裂解酶；ArgF`：乙酰鸟氨酸氨甲酰转移酶；ArgJ：鸟氨酸乙酰转移酶）

Fig. 1 The biosynthetic pathways of ʟ-arginine in microorganisms (ArgA: acetylglutamate synthase; ArgB: acetylglutamate kinase; ArgC: acetyl-glutamyl-phosphate reductase; ArgD: acetylornithine aminotransferase;ArgE: acetylornithine deacetylase; ArgF: ornithine carbamoyltransferase; ArgG: argininosuccinate synthase; ArgH: argininosuccinate lyase; ArgF`: acetylornithine carbamoyltransferase;ArgJ: ornithine acetyltransferase)