近十年天然产物药物的生物合成研究进展

冯金, 潘海学, 唐功利

Research advances in biosynthesis of natural product drugs within the past decade

Jin FENG, Haixue PAN, Gongli TANG

图18 秋水仙碱的生物合成途径 （蓝色为新表征的酶）OMT1/2/3/4—O-甲基转移酶；NMT—N-甲基转移酶；CYP75A109/75A110/71FB1—细胞色素P450

Fig. 18 Biosynthetic pathway of colchicine (Newly characterized enzymes are highlighted in blue) OMT1/2/3/4—O-methyltransferases; NMT—N-methyltransferase; CYP75A109/75A110/71FB1—cytochromes P450