蛋白质工程在医药产业中的应用

温艳华, 刘合栋, 曹春来, 巫瑞波

Applications of protein engineering in pharmaceutical industry

WEN Yanhua, LIU Hedong, CAO Chunlai, WU Ruibo

图2 LovD9利用非天然酰基供体DMB-S-MMP催化monacolin J的酰化合成辛伐他汀

Fig. 2 LovD9 catalyzing the acylation of monacolin J to produce simvastatin with the non-natural acyl donor DMB-S-MMP