蛋白质工程在医药产业中的应用

温艳华, 刘合栋, 曹春来, 巫瑞波

Applications of protein engineering in pharmaceutical industry

WEN Yanhua, LIU Hedong, CAO Chunlai, WU Ruibo

图3 二步三酶法制备阿托伐他汀的中间体羟基腈

Fig. 3 Process for producing hydroxynitrile through the catalysis of three enzymes (GDH, KRED, and HHDH)