蛋白质工程在医药产业中的应用

温艳华, 刘合栋, 曹春来, 巫瑞波

Applications of protein engineering in pharmaceutical industry

WEN Yanhua, LIU Hedong, CAO Chunlai, WU Ruibo

图5 青霉素G酰化酶的定向进化实现胰岛素特定位置的生物偶联

Fig. 5 Directed evolution of penicillin G acylase enables the site-selective bioconjugation of insulin