光遗传学工具在学习记忆中的应用研究

郑益坤, 郑婕, 胡国鹏

Research on the application of optogenetic tools in learning and memory

ZHENG Yikun, ZHENG Jie, HU Guopeng

图1 突触连接强化示意图 （图中展示神经元A、R和B之间的突触连接如何通过重复的电生理刺激得到增强。该过程模拟信息的重复编码机制，并反映了形成长期记忆的基本原理。根据Hebb法则，如果两个神经元频繁且近距离地共同活动，相关突触连接将得到加强，从而提高信息传递的效率并增强突触后的反应能力）

Fig.1 Diagram of strengthening synaptic connections (The diagram illustrates how synaptic connections between neurons A, R, and B are strengthened through repeated electrophysiological stimulations. This process simulates the mechanism of repeated encoding of information and reflects the fundamental principles of long-term memory formation. According to Hebb’s rule, if two neurons frequently and closely act together, the associated synaptic connections will be strengthened, thereby improving the efficiency of information transmission, and enhancing the postsynaptic response.)