Synthetic Biology Journal ›› 2023, Vol. 4 ›› Issue (4): 676-689.DOI: 10.12211/2096-8280.2023-002
• Invited Review • Previous Articles Next Articles
Kai WANG1, Wan ZHANG2, Yunhai HUANG3, Lixin ZHANG3, Chunbo LOU1
Received:
2023-01-01
Revised:
2023-02-27
Online:
2023-09-14
Published:
2023-08-31
Contact:
Lixin ZHANG, Chunbo LOU
王凯1, 张婉2, 黄云海3, 张立新3, 娄春波1
通讯作者:
张立新,娄春波
作者简介:
基金资助:
CLC Number:
Kai WANG, Wan ZHANG, Yunhai HUANG, Lixin ZHANG, Chunbo LOU. Application of phage therapy in the treatment of intracellular pathogens[J]. Synthetic Biology Journal, 2023, 4(4): 676-689.
王凯, 张婉, 黄云海, 张立新, 娄春波. 噬菌体疗法在胞内病原菌治疗中的挑战与思考[J]. 合成生物学, 2023, 4(4): 676-689.
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URL: https://synbioj.cip.com.cn/EN/10.12211/2096-8280.2023-002
细胞内病原菌 | 噬菌体 | 实验模型/细胞类型 | 文献来源 | 研究阶段 |
---|---|---|---|---|
Chlamydia psittaci | phiCPG1 | HeLa cells | Hsia et al, 2000[ | Preclinical Research |
Staphylococcus aureus | MSa | Peritoneal mouse macrophages/mice | Capparelli et al, 2007[ | Preclinical Research |
MR-5 | Peritoneal mouse macrophages | Kaur et al, 2014[ | Preclinical Research | |
vB_SauM_JS25 | Bovine Mammary Epithelial Cells (MAC-T) | Zhang et al, 2017[ | Preclinical Research | |
MR-5 and MR-10 | mice | Chhibber et al, 2018[ | Preclinical Research | |
PP1493, PP1815, and PP1957 | MG63 osteoblastic Cells | Kolenda et al, 2020[ | Preclinical Research | |
Burkholderia pseudomallei | C34 | mice | Guang-Han et al, 2016[ | Preclinical Research |
Escherichia coli | K1F | Urinary bladder epithelial cell line, T24 (HTB-4) | Møller-Olsen et al, 2018[ | Preclinical Research |
K1F | human cerebral microvascularendothelial cells (hCMEC) | Møller-Olsen et al, 2020[ | Preclinical Research | |
Klebsiella pneumoniae | KPO1K2 | Peritoneal mouse macrophages | Singha et al, 2005[ | Preclinical Research |
KØ1, KØ2, KØ3, KØ4 and KØ5 | mice | Chadha et al, 2017[ | Preclinical Research | |
M. tuberculosis /Mycobacterium avium | TM4 | Mouse peritoneal macrophage cell line, RAW 264.7 | Broxmeyer et al, 2002[ | Preclinical Research |
Mycobacterium avium | TM4 | mice | Danelishvili et al, 2006[ | Preclinical Research |
M. tuberculosis | DS-A | pigs | Zemskova et al, 1991[ | Preclinical Research |
D29 | mouse peritoneal macrophages | Peng et al, 2006[ | Preclinical Research | |
D29 | macrophages | Xiong et al, 2014[ | Preclinical Research | |
D29 | mice | Carrigy et al, 2017[ | Preclinical Research | |
D29 | Peritoneal mouse macrophages | Lapenkova et al, 2018[ | Preclinical Research | |
D29 | mice | Carrigy et al, 2019[ | Preclinical Research |
Table 1 Phages against intracellular bacterial infection.
细胞内病原菌 | 噬菌体 | 实验模型/细胞类型 | 文献来源 | 研究阶段 |
---|---|---|---|---|
Chlamydia psittaci | phiCPG1 | HeLa cells | Hsia et al, 2000[ | Preclinical Research |
Staphylococcus aureus | MSa | Peritoneal mouse macrophages/mice | Capparelli et al, 2007[ | Preclinical Research |
MR-5 | Peritoneal mouse macrophages | Kaur et al, 2014[ | Preclinical Research | |
vB_SauM_JS25 | Bovine Mammary Epithelial Cells (MAC-T) | Zhang et al, 2017[ | Preclinical Research | |
MR-5 and MR-10 | mice | Chhibber et al, 2018[ | Preclinical Research | |
PP1493, PP1815, and PP1957 | MG63 osteoblastic Cells | Kolenda et al, 2020[ | Preclinical Research | |
Burkholderia pseudomallei | C34 | mice | Guang-Han et al, 2016[ | Preclinical Research |
Escherichia coli | K1F | Urinary bladder epithelial cell line, T24 (HTB-4) | Møller-Olsen et al, 2018[ | Preclinical Research |
K1F | human cerebral microvascularendothelial cells (hCMEC) | Møller-Olsen et al, 2020[ | Preclinical Research | |
Klebsiella pneumoniae | KPO1K2 | Peritoneal mouse macrophages | Singha et al, 2005[ | Preclinical Research |
KØ1, KØ2, KØ3, KØ4 and KØ5 | mice | Chadha et al, 2017[ | Preclinical Research | |
M. tuberculosis /Mycobacterium avium | TM4 | Mouse peritoneal macrophage cell line, RAW 264.7 | Broxmeyer et al, 2002[ | Preclinical Research |
Mycobacterium avium | TM4 | mice | Danelishvili et al, 2006[ | Preclinical Research |
M. tuberculosis | DS-A | pigs | Zemskova et al, 1991[ | Preclinical Research |
D29 | mouse peritoneal macrophages | Peng et al, 2006[ | Preclinical Research | |
D29 | macrophages | Xiong et al, 2014[ | Preclinical Research | |
D29 | mice | Carrigy et al, 2017[ | Preclinical Research | |
D29 | Peritoneal mouse macrophages | Lapenkova et al, 2018[ | Preclinical Research | |
D29 | mice | Carrigy et al, 2019[ | Preclinical Research |
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